Design, synthesis, spectral analysis & antibacterial activity of thiazol - pyrimidine 5-carboxamide derivatives

Abstract

Several fused heterocycles based on thiazolidinone derivatives were synthesized and characterized using physical properties, elemental analysis, IR and other spectral studies. New ligands i.e. 4-(2-furyl)-6-methyl-2-oxo-thiazol- pyrimidine-5-carboxamidewere synthesized  by  condensation reaction  of  thiazolidinone derivatives  with  phenyl hydrazine in presence of glacial acetic acid. Furthermore the antibacterial of newly synthesized fused heterocyclic compounds was examined against various microbial strains.